Persephacin excels as broad-spectrum antifungal
Persephacin, a novel fungal isolate, strongly inhibits a broad range of pathogenic fungi while exhibiting low cytotoxicity to mammalian cells.
Persephacin contains unique structural elements that diminishes its susceptibility to efflux, and enables it to inhibit difficult-to-treat yeast and filamentous fungal pathogens, including drug-resistant fungi. This new antifungal agent has outperformed natamycin against candida and several aspergillus pathogens. This technology offers a new broad-spectrum antifungal agent, which is readily sourced from a natural product.